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Probiotic Combination capsule (9 Billion): Uses,Dosage,Side Effects

Generic Name
Probiotic Combination (9 Billion)
Therapeutic Class: Probiotic

Indications:
This is indicated for the management of gastrointestinal problems e.g. IBS, constipation, flatulence, indigestion, etc.

Presentation:
Each capsule contains-
  • Lactobacillus acidophilus 2.25 billion
  • Lactobacillus bulgaricus 75 million
  • Lactobacillus lactis 2.1 billion
  • Lactobacillus casei 2.25 billion
  • Streptococcus thermophilus 300 million
  • Bifidobacterium bifidum 450 million
  • Bifidobacterium longum 75 million
  • Bifidobacterium infantis 1.5 billion
  • Fructo-Oligosaccharides 50 mg
  • soy fiber & papaya extract 140 mg.
Description:
Probiotics have antimicrobial, immunomodulatory, antidiarrheal, antiallergic, and antioxidant activities. Probiotics have been used with some benefit in the prevention and treatment of some gastrointestinal disorders, including antibiotic-associated diarrhea and some infectious and viral diarrhea, most notably rotavirus-induced diarrhea in infants and children, lactose intolerance, sucrase, and maltase deficiencies, and inflammatory bowel disease. Soy is a dietary supplement that is used to prevent heart disease. Other uses include the treatment of menopause symptoms, like hot flashes. Soy may also be used to treat osteoporosis, high cholesterol (fat in the blood), kidney disease, and arthritis. Papayas contain an enzyme called papain that aids digestion. It is also high in fiber and water content, both of which help to prevent constipation and promote regularity and a healthy digestive tract. Fructo-oligosaccharides appear to be of benefit in modulating the microbial ecology of the gut, boosting gastrointestinal immunity. FOS may also protect against colon cancer and may also aid in calcium absorption.

Pharmacology:
The antimicrobial activity of probiotics is thought to be accounted for, in large part, by their ability to colonize the colon and reinforce the barrier function of the intestinal mucosa. In addition, some probiotics have been found to secrete antimicrobial substances known as bacteriocins. It reduced gastrointestinal pH through stimulation of lactic acid-producing bacteria and provides a direct antagonistic action on GI pathogen. Lactobacillus acidophilus, Lactobacillus bulgaricus and Bifidobaterium, have also demonstrated antioxidative ability. Mechanisms include chelation of metal ions (iron, copper), scavenging of reactive oxygen species, and reducing activity.

Dosage & Administration:
Adults and children over six years of age: one capsule 2 to 3 times daily or as advised by a physician.

Contraindications:
Probiotics are contraindicated in those who are hypersensitive to any component of a probiotic-containing product.

Side Effects
:
Probiotics are generally well tolerated.

Pregnancy & Lactation:
Should be used with caution or seek the advice of a healthcare professional before use.

Storage:
Store below 15°C, cool and dry place, away from direct sunlight & moisture. To maintain optimum shelf life and potency store in the refrigerator. Keep the medicine out of reach of children.

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