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Vitamin B1, B6 & B12: Uses,Dosage,Side Effects

Generic Name
Vitamin B1, B6 & B12
Therapeutic Class: Specific combined vitamin preparations

Indications:
This combination could also be used in-
  • Chronic pains like sciatica
  • Lumbago
  • Trigeminal neuralgia
  • Facial paralysis
  • Optic neuritis
  • As well as neuropathy & cardiac complications. Besides these, this mix could also be utilized in the deficiency of those vitamins.
Each film-coated tablet contains-
Vitamin B1 (Thiamine Mononitrate) 100 mg
Vitamin B6 (Pyridoxine Hydrochloride) 200 mg
Vitamin B12 (Cyanocobalamin) 200 micrograms.

Each 3 ml ampoule contains-
Thiamine Hydrochloride (Vitamin B1) 100 mg
Pyridoxine Hydrochloride (Vitamin B6) 100 mg
Cyanocobalamin (Vitamin B12) 1000 mcg.

Pharmacology:
This is a combined preparation of vitamin B1 (Thiamine Mononitrate), vitamin B6 (Pyridoxine Hydrochloride), and vitamin B12 (Cyanocobalamin). These vitamins play an important role as co-enzyme within the metabolism of systema nervosum. supports the regeneration of nerve fibers and medullary sheath by activation of the neuron metabolism and therefore the natural repair mechanism.

Dosage & Administration:
Tablets: 1 to three tablets per day or as directed by the physician.
Injection: Ampules are preferably injected intramuscularly (deep intragluteal). In severe cases, 1 ampoule daily until the acute symptoms subside. For milder cases and follow up therapy 2 to three ampoules per week.

Interaction:
Vitamin B6 (Pyridoxine Hydrochloride) reduces the therapeutic effect of Levodopa but it doesn't occur if a dopa decarboxylase inhibitor is additionally given. Neomycin, Chloramphenicol, Aminosalicylic acid & H2 receptor antagonists may reduce vitamin B12 absorption.

Contraindications:
It shouldn't be utilized in patients with known hypersensitivity to Thiamine, Cobalt, or the other component of those preparations.

Side Effects:
Very rarely allergy and sensitivity disturbance may occur.

Pregnancy & Lactation:
No risks became known related to the utilization of this mix during pregnancy at the recommended dosage. vitamin B1, B6 & B12 are secreted into the breast milk but risks of overdose for the infant aren't known.

Precautions & Warnings:
It should be avoided just in case of hypersensitivity to Thiamine, Cobalt, or the other component of those preparations. Cyanocobalamin shouldn't tend before a diagnosis has been fully established due to the masking symptoms of subacute degeneration of the medulla spinalis.

Storage:
Keep in a dry place far away from light and warmth. exclude the reach of Children's.

Brand Names

Brand Name

Company

Strength 

Neobion

Aristopharma Ltd.

100 mg+200 mg+200 mcg

Neurocare

Beximco Pharmaceuticals Ltd.

100 mg+200 mg+200 mcg

Vitabion

Incepta Pharmaceuticals Ltd.

100 mg+200 mg+200 mcg

Neuro-B

Square Pharmaceuticals Ltd.

100 mg+200 mg+200 mcg

Myelin

Opsonin Pharma Ltd.

100 mg+200 mg+200 mcg

B126

Popular Pharmaceuticals Ltd.

100 mg+200 mg+200 mcg


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