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Folic Acid + Zinc Sulfate Monohydrate: Uses, Dosage, Side Effects

Generic Name
Folic Acid + Zinc Sulfate Monohydrate
Therapeutic Class: Specific mineral & vitamin combined preparations

Indications
This tablet is indicated for the treatment and prophylaxis of Folic Acid and Zinc deficiencies.

Pharmacology
This tablet is a special preparation of Folic Acid & Zinc Sulfate Monohydrate. Zinc is an essential trace element required for human nutrition and involved in a number of body enzyme system. Severe Zinc deficiency causes skin lesion, alopecia, diarrhoea, increased susceptibility of infections, cognitive impairment, etc. Folic Acid is a member of the B-Vitamins group. It is reduced in the body to tetrahydrofolate, which is the coenzyme for various metabolic processes including the synthesis of purine and pyrimidine nucleotides, and hence the synthesis of DNA. It is also involved in some amino acid conversions. Deficiency of Folic Acid may cause megaloblastic anaemia, develops when the dietary intake is inadequate, as in malnutrition, from malabsorption, from increased utilization as in pregnancy of conditions such as haemolytic anaemia, and as a result of administration of folate antagonists.

Dosage & Administration
Orally 1 tablet daily or as directed by the physician.

Interaction
A large amount of Calcium decreases the absorption of Zinc. In case of Folic Acid, no drug interactions have been reported.

Contraindications
Zinc is contraindicated in patients having hypersensitivity to Zinc. Folic Acid is contraindicated in untreated cobalamine deficiency

Side Effects
Folic Acid & Zinc is well tolerated in the recommended dose. Occasionally gastrointestinal disturbances like abdominal pain, dyspepsia, nausea, vomiting, fever and respiratory distress may occur.

Pregnancy & Lactation
Recommended during pregnancy & lactation.

Overdose Effects
Zinc Sulfate is corrosive in overdose. Symptoms are corrosion and inflammation of the mucous membrane of the mouth and stomach.

Storage 
Store at temperature of below 30°C, protect from light & moisture. Keep out of reach of children.

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