Ketoconazole (Shampoo)
Therapeutic Class: Skin / Drugs for subcutaneous and mycoses
Indications:
ketoconazole 2% shampoo is indicated for the treatment and prophylaxis of infections in which the yeast Malassezia (previously called Pityrosporum) is involved, such as pityriasis Versicolor (localized), seborrhoeic dermatitis, and pityriasis capitis (dandruff).
Presentation:
Shampoo: Each gram shampoo contains Ketoconazole BP 20 mg
Description:
Dosage & Administration:
To use the Ketoconazole 2% shampoo, follow these steps:
Indications:
ketoconazole 2% shampoo is indicated for the treatment and prophylaxis of infections in which the yeast Malassezia (previously called Pityrosporum) is involved, such as pityriasis Versicolor (localized), seborrhoeic dermatitis, and pityriasis capitis (dandruff).
Presentation:
Shampoo: Each gram shampoo contains Ketoconazole BP 20 mg
Description:
Ketoconazole, a synthetic imidazole dioxolane derivative, has potent antifungal activity against dermatophytes, such as Trichophyton sp., Epidermophyton sp., Microsporum sp., and yeasts, such as Candida sp. and Malassezia spp. (Pityrosporum spp). Ketoconazole 2% shampoo rapidly relieves scaling and pruritus, which are usually associated with Seborrhoeic dermatitis, Pityriasis capitis (dandruff), and Pityriasis Versicolor.
To use the Ketoconazole 2% shampoo, follow these steps:
- Shake the bottle well before use
- Use a small amount of water to wet the area where Ketoconazole 2% shampoo is to be applied
- Apply the shampoo to the affected skin/scalp and a large area around it
- Use fingers to rub the shampoo until it forms lather
- Leave the shampoo on skin/scalp for 5 minutes
- Rinse the shampoo off skin/scalp with water
Interaction:
No information was found for the Shampoo form of Ketoconazole.
Contraindications:
Contraindicated in patients with known hypersensitivity to ketoconazole.
Side Effects:
Topical treatment with ketoconazole shampoo 2% is generally well tolerated. As with other shampoos, a local burning sensation, itching, or contact dermatitis (due to irritation or allergy) may occur on exposed areas. Oily and dry hair have been reported rarely with the use of ketoconazole shampoo 2%.
Pregnancy & Lactation:
Since ketoconazole is not absorbed through the skin after topical application, pregnancy and lactation are not a contraindication for the use of ketoconazole shampoo 2%.
Precautions & Warnings:
In patients who have been on prolonged treatment with topical corticosteroids, it is recommended that the steroid therapy be gradually withdrawn over a period of 2 to 3 weeks, while using ketoconazole shampoo 2%, to prevent any potential rebound effect. Increased hair shedding is often associated with seborrhoeic dermatitis and dandruff, and has been rarely reported with the use of ketoconazole shampoo 2%. Avoid contact with the eyes. If the shampoo should get into the eyes, it should be bathed with water.
Overdose:
Not expected as ketoconazole shampoo 2% is intended for external use only. In the event of accidental ingestion, only supportive measures should be carried out. To avoid aspiration, emesis or gastric lavage should not be performed.
Storage:
Store in a cool and dry place, protected from light.
No information was found for the Shampoo form of Ketoconazole.
Contraindications:
Contraindicated in patients with known hypersensitivity to ketoconazole.
Side Effects:
Topical treatment with ketoconazole shampoo 2% is generally well tolerated. As with other shampoos, a local burning sensation, itching, or contact dermatitis (due to irritation or allergy) may occur on exposed areas. Oily and dry hair have been reported rarely with the use of ketoconazole shampoo 2%.
Pregnancy & Lactation:
Since ketoconazole is not absorbed through the skin after topical application, pregnancy and lactation are not a contraindication for the use of ketoconazole shampoo 2%.
Precautions & Warnings:
In patients who have been on prolonged treatment with topical corticosteroids, it is recommended that the steroid therapy be gradually withdrawn over a period of 2 to 3 weeks, while using ketoconazole shampoo 2%, to prevent any potential rebound effect. Increased hair shedding is often associated with seborrhoeic dermatitis and dandruff, and has been rarely reported with the use of ketoconazole shampoo 2%. Avoid contact with the eyes. If the shampoo should get into the eyes, it should be bathed with water.
Overdose:
Not expected as ketoconazole shampoo 2% is intended for external use only. In the event of accidental ingestion, only supportive measures should be carried out. To avoid aspiration, emesis or gastric lavage should not be performed.
Storage:
Store in a cool and dry place, protected from light.