Generic Names
Betamethasone + Gentamicin
Betamethasone + Gentamicin
Therapeutic Class: Other Topical corticosteroids
Indications:
Treatment of corticosteroid reactive dermatitis is complicated when a secondary infection causes a secondary infection or when the possibility of such an infection is suspected. It is recommended to use the cream for wet, early infections, and minor infections such as sticky, odorous acne, or infected seborrheic dermatitis. The ointment helps retain moisture and is effective for dry eczema or psoriatic skin infections.
Description:
Betamethasone Dipropionate with antibiotic combines the medicinal drug, topical anesthetic, and vasoconstrictor activity of an artificial sex hormone, betamethasone Dipropionate, with the broad spectrum anti-bacterial result of antibiotic.In secondary skin infections, antibiotic facilitates the treatment of the underlying skin disorder by dominant the infection. bacterium prone to the action of antibiotic embody sensitive strains of streptococci (group A beta lysis, alpha-hemolytic), S. aureus (coagulase-positive, enzyme negative, and a few enzyme manufacturing strains), and also the gram-negative bacterium P.aeruginosa, E.aerogenes, E. coli, Proteus (both indole positive and indole negative), K. pneumoniae, and S.marcescens.
This cream is slightly acidic so it's inside the pH scale vary of the traditional skin. On application, it leaves minimum residue while not viscousness or fat-ness. The presence of a mixture in each cream and ointment offers lubricating qualities and helps to forestall excessive drying.
Dosage & Administration:
An adequate amount of the cream or ointment ought to be applied to hide utterly the affected space and will be massaged gently and entirely into the skin. The same old frequency of application is doubly daily though some patients could also be maintained adequately with less frequent application.
Contraindications:
Viral diseases as well as vaccinia, varicella, herpes simplex, plant life infections, T.B. of the skin, and hypersensitivity to any of the parts.
Side Effects:
The following native adverse skin reactions are according to the utilization of topical steroids: waterlessness, itching, burning, native irritation, striae, skin atrophy, hypertrichosis, amendment in pigmentation, and secondary infection. Adrenal suppression has conjointly been according to the following topical sex hormone medical aid. Posterior subcapsular cataracts are according to the general use of corticosteroids.
Pregnancy & Lactation:
Since the safety of topical sex hormone use in pregnant ladies has not been established, medicine of this category ought to be used throughout the physiological state providing the potential profit justifies the potential risk to the vertebrate. medicine of this category mustn't be used extensively in giant amounts or for prolonged periods of your time in pregnant patients. Since it's not illustrious whether or not topical administration of corticosteroids may result in adequate general absorption to provide detectable quantities in breast milk, a decision ought to be created to discontinue nursing or to discontinue the drug, taking into consideration the importance of the drug to the mother. This drug mustn't be employed in or close to the eyes since the vehicle isn't developed for ophthalmic use.
Precautions & Warnings:
Gentamicin isn't effective against fungi, yeasts, or viruses. Patients with superficial plant life or yeast infections conjointly should receive specific medical aid and also the use of the drug could need to be interrupted. the utilization of such topical preparations could end in an associate degree overgrowth of non-susceptible organisms. Suitable precautions ought to be taken in victimization topical corticosteroids in patients with stasis eczema and alternative skin diseases with impaired circulation.
Prolonged use of sex hormone preparations could turn out striae or atrophy of the skin or s.c. tissue. If this happens, treatment ought to be interrupted. Causal factors ought to be sought-after associate degreed eliminated whenever doable and also the sensitivity of an infecting organism to antibiotic ought to be verified.
Patients ought to be suggested to tell the resulting physicians of the previous use of corticosteroids.
While no general effects are discovered following the topical application of antibiotics, ototoxic general concentrations will cause permanent impairment of proprioception to operate within the presence of a renal disorder or existing eighth nervous harm.
Caution ought to be exercised if an antibiotic is employed in people UN agency square measure illustrious to be sensitive to locally applied antibacterials. If irritation or sensitization develops, treatment ought to be interrupted.
Application over in-depth lesions could end in vital general absorption manufacturing hypercortisolism manifesting itself by adrenal suppression, moon face, striae, and suppression of growth in children.
Patients ought to be followed up often, and also the product ought to be interrupted once the infection has cleared.
Occlusive dressing mustn't be used.
Overdose Effects:
Symptoms: Excessive prolonged use of topical corticosteroids will suppress pituitary-adrenal operate resulting in secondary adrenal insufficiency.
Treatment: Correct solution imbalance, if needed. Slow withdrawal of corticosteroids could also be required.
Storage:
Store between 2-30° C.