METOCLOPRAMIDE
METOCLOPRAMIDE HCl: Tablet/syrup/drop/injection
It is an effective anti-emetic drug. It has got a central anti-emetic effect & a peripheral action on the gut as a dopamine antagonist, as a result, it enhances the motility of the upper gastrointestinal tract & thus hastens gastric emptying.
Indications: Non-ulcer dyspepsia, for speeding the transit of barium during intestinal follow-through examination.reflux oesophagitis and also in non-specific or cytotoxic nausea and vomiting.
Side Effects: Extrapyramidal reactions, drowsiness, constipation, gynecomastia, galactorrhoea.
Cautions: Renal impairment, immediately after abdominal surgery, Parkinsonism & children.
Adult: 15 to 20 years 5-10mg; others, 10mg. Both 3 times daily.
Child: Under 1 yr, 1 mg twice daily; 1-3 yrs. Img 2 or 3 times daily; 3-5 yrs. 2mg 2 or 3 times daily;5-14 yrs. 2.5-5mg 3 times daily. All orally, i.m or i.v. Usual max. doses, all ages 0.5mg/kg body-daily
Preparations: See under anti-vomiting drugs in the chapter of CNS products.